随着减重药巨头诺和诺德重磅GLP-1类药物司美格鲁肽在中国的核心分子专利即将于3月到期，一大批中国本土的司美格鲁肽仿制药正在获批路上。据公开信息，目前国内市场上包括九源基因、丽珠集团、华东医药、齐鲁制药、正大天晴在内的十多家本土制药公司的司美格鲁肽仿制药有望在不久的将来上市，还有十余款处于三期临床，一场价格大战即将席卷。一位内分泌专家表示，随着更多仿制药的上市，减重药很快就会迎来“白菜价”时代。（第一财经）
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Finding these optimization opportunities can itself be a significant undertaking. It requires end-to-end understanding of the spec to identify which behaviors are observable and which can safely be elided. Even then, whether a given optimization is actually spec-compliant is often unclear. Implementers must make judgment calls about which semantics they can relax without breaking compatibility. This puts enormous pressure on runtime teams to become spec experts just to achieve acceptable performance.